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### Topology in Molecular Biology Michael I. Monastyrsky

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### DNA Topology Fundamentals Tufts University

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Geometry deals with quantitative properties of space, such as distance and curvature on manifolds. Topology deals with more qualitative properties of space, namely Knot theory, a branch of topology, is used in biology to study the effects of certain enzymes on DNA. These enzymes cut, twist, and reconnect the DNA, causing knotting with observable effects such as slower electrophoresis.

The focus of this contribution is on biological applications of topology to the study of DNA structure and to understanding proteinвЂ“DNA interactions that involve alterations of DNA topology. Control of DNA topology is an essential aspect of the existence of every living cell because of the extraordinary degree Pris: 1649 kr. HГ¤ftad, 2010. Skickas inom 11-20 vardagar. KГ¶p Topology in Molecular Biology av Michael I Monastyrsky pГҐ Bokus.com.

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